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William A Friedman, MD : Research

Neurosurgeon, Spine Surgeon

Photo of William A Friedman

Research at a glance

Top areas of exploration

  • Radiosurgery , 99 publications
  • Brain Neoplasms , 51 publications
  • Intracranial Arteriovenous Malformations , 31 publications
  • Stereotaxic Techniques , 27 publications

Research activity

212 publications

14,127 citations

Why is this important?

Focus

In 1986, Friedman began collaborative work with Francis J. Bova, Ph.D., which led to the development of the patented UF radiosurgery system. The system, known as LINAC Scalpel, assists with localizing, planning and treating intracranial tumors using computer software and a specially designed linear accelerator. The LINAC Scalpel has become one of the most popular commercial radiosurgery systems worldwide and has improved the accuracy of high-dose radiation delivered to brain tumors, with very little of the dose reaching normal brain structures. Friedman and Bova received the 1990 UF College of Medicine Clinical Research Prize in recognition of this accomplishment. Friedman is the leader of a multidisciplinary radiosurgery team, which has treated more than 4600 patients, published more than 175 papers and chapters, produced many international meetings and educated hundreds of visiting physicians.

My publications

212 publications

2025

A Comparison of Radiosurgical Planning Techniques for the Treatment of Trigeminal Neuralgia.

Practical radiation oncology

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2024

Stereotactic Radiosurgery for Vestibular Schwannoma With Radiographic Brainstem Compression.

American journal of clinical oncology

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2022

Repeat single-fraction stereotactic radiosurgery for recurrent vestibular schwannoma.

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

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2018

A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence.

Cell reports

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2018

Long-term Outcomes After Radiosurgery for Temporal Bone Paragangliomas.

American journal of clinical oncology

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