S-531011 as Monotherapy and in Combination With an Immune Checkpoint Inhibitor in Advanced or Metast
The primary objective of Part A is to evaluate the safety and tolerability of S-531011 and to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) of S-531011.
The primary objective of Parts B and C is to evaluate the�
- Investigator
- Thomas J George
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
Phase 1/1B Study of DS-8201a and AZD6738 in Advanced Solid Tumors With HER2 Expression
The dose escalation phase of this trial identifies the safety, side effects and best dose of ceralasertib (AZD6738) when given in combination with trastuzumab deruxtecan (DS-8201a) in treating patients with solid tumors that have a change (mutation)�
- Investigator
- Thomas J George
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
ROSANNA
This study will investigate whether short-term daily energy drink consumption results in an increase in hydrogen sulfide-producing bacteria in adults 18-40 years old.
- Investigator
- Thomas J George
- Status
- Accepting Candidates
- Ages
- 18 Years - 40 Years
- Sexes
- All