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Michael J Haller, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Michael J Haller

Research at a glance

Top areas of exploration

  • Diabetes Mellitus, Type 1 , 67 publications
  • Glycated Hemoglobin , 15 publications
  • Insulin , 15 publications
  • Blood Glucose , 14 publications

Research activity

139 publications

3,377 citations

Why is this important?

Focus

Dr. Haller's research focuses on predicting, preventing, and ultimately reversing type 1 diabetes through his participation in numerous clinical trials utilizing immunotherapies. Dr. Haller serves as the Principal Investigator for the University of Florida TrialNet Clinical Center, Chair of the TEDDY Clinical Implementation Committee, and PI of the UF/Stanford ECHO Collaborative. Dr. Haller also leads and participates in technology studies seeking to improve the lives of people living with diabetes through the use of pumps, continuous glucose monitors, and systems that automate insulin delivery.

Active clinical trials

FABULINUS

This is a randomized, parallel group, double-blind Phase 2 study with a 52-week blinded extension evaluating the safety and efficacy of 3 dose levels of frexalimab in comparison with placebo in participants with newly diagnosed T1D on insulin鈥�

Investigator
Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
TN-31 JAKPOT T1D

A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
12 Years - 35 Years
Sexes
All
Protocol TN-25

The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to鈥�

Investigators
Laura Jacobsen, Michael J Haller
Status
Accepting Candidates
Ages
8 Years - 45 Years
Sexes
All

My publications

139 publications

2025

Considerations for more actionable consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Reply to Mallone R [letter]

Diabetologia

2025

Developing an automated algorithm for identification of children and adolescents with diabetes using electronic health records from the OneFlorida+ clinical research network.

Diabetes, obesity & metabolism

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2025

Emerging Immunotherapies for Disease Modification of Type 1 Diabetes.

Drugs

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2025

Looking back at the TEDDY study: lessons and future directions

Nature Reviews Endocrinology

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2025

Project ECHO Diabetes Trial Improves Outcomes for Medically Underserved People

Diabetes Care

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