Medulloblastoma Adoptive T cell therapy, DC vaccines, and Hematopoietic stem cells MATCHPOINT
This is a pilot study in a small number of children and young adults with relapsed/progressive medulloblastoma (MB) looking at the feasibility and safety of adoptive cell therapy plus PD-1 blockade.
- Investigators
- John A Ligon, Marcia B Hodik
- Status
- Accepting Candidates
- Ages
- 4 Years - 30 Years
- Sexes
- All
Tinks Trial
The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docetaxel) can improve outcomes in people with鈥�
- Investigator
- John A Ligon
- Status
- Accepting Candidates
- Ages
- 2 Years - 40 Years
- Sexes
- All
OMS721-HCT-002
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).
- Investigator
- John A Ligon
- Status
- Accepting Candidates
- Ages
- 28 Days - 17 Years
- Sexes
- All