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Serena Guo is an Assistant Professor in the Department of Pharmaceutical Outcomes and Policy at the University of Florida (UF) College of Pharmacy. She also has a secondary affiliation with the Department of Health Outcomes and Biomedical Informatics, UF College of Medicine.

Dr. Guo conducts research in pharmacoepidemiology and pharmacoinformatics, primarily focused on cardiometabolic diseases, neurodegenerative conditions (e.g., dementia) and cancer, with the goal of promoting precision therapeutics and health equity. Her research draws on large real-world data (e.g., electronic health records and insurance claims data) and advanced analytics (e.g., AI/machine learning, causal-principled modeling, and geospatial analyses) to: 1) assess comparative effectiveness/safety and heterogeneous treatment effects (HTEs) of treatments and interventions using target trial emulations, and 2) develop intelligent clinical decision support tools to be integrated into clinical care. Dr. Guo has published over 110 peer-reviewed manuscripts. Several articles have been published in top-tier journals, including Annals of Internal Medicine, Nature Communications, and JAMA Neurology, and featured in media outlets, including the Washington Post, NPR, and CNN. Her research programs and collaborations have been funded by the NIDDK, NIA, NIMHD, Veterans Affairs, CDC, and the PhRMA Foundation.