OPTIMUS PRIME - Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa
In this study we are evaluating the safety and feasibility of the triple combination (TTFields, MLA, pembrolizumab) in adult patients diagnosed with recurrent or progressive glioblastoma (GBM) WHO Grade IV, IDH wild type or recurrent or progressive鈥�
- Investigator
- Ashley Ghiaseddin
- Status
- Accepting Candidates
- Ages
- 18 Years - 90 Years
- Sexes
- All
EF-41/KEYNOTE
This is a multicenter, two-arm, randomized, double-blind, placebo-controlled study of Optune庐 (Tumor Treating Fields at 200 kHz) together with maintenance Temozolomide (TMZ) chemotherapy agent and pembrolizumab compared to Optune庐 together with鈥�
- Investigator
- Ashley Ghiaseddin
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
IMPACT; Phase I Study of IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ Adult GBM
This is a phase I study to assess the safety and feasibility of IL-8 receptor modified patient-derived activated CD70 CAR T cell therapy in CD70+ adult glioblastoma
- Investigator
- Ashley Ghiaseddin
- Status
- Accepting Candidates
- Ages
- 18 Years - 80 Years
- Sexes
- All