This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - N/A
- Sexes
- All
A cyst is a closed pocket or pouch of tissue. It can be filled with air, fluid, pus, or other material.
Cysts may form within any tissue in the body. Most cysts in the lungs are filled with air. Cysts that form in the lymph system or kidneys are fluid-filled. Certain parasites, such as some types of roundworms and tapeworms, can form cysts within the muscles, liver, brain, lungs, and eyes.
Cysts are common on the skin. They can develop when acne causes a sebaceous gland to clog, or they can form around something that is stuck in the skin. These cysts are not cancer (benign), but can cause pain and changes in appearance. At times, they can become infected and need treatment due to pain and swelling.
Cysts can be drained or removed with surgery, depending on their type and location.
Sometimes, a cyst looks like a skin cancer and may need to be removed to be tested.
A pilonidal dimple or cyst is a type of skin cyst at the top of the buttocks in the midline of the body.
Dinulos JGH. Principles of diagnosis and anatomy. In: Dinulos JGH, ed. Habif's Clinical Dermatology: A Color Guide in Diagnosis and Therapy. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 1.
Fairley JK, King CH. Tapeworms (cestodes). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 289.
James WD, Elston DM, Treat JR, Rosenbach MA, Neuhaus IM. Epidermal nevi, neoplasms, and cysts. In: James WD, Elston DM, Treat JR, Rosenbach, MA, Neuhaus IM, eds. Andrews' Diseases of the Skin: Clinical Dermatology. 13th ed. Philadelphia, PA: Elsevier; 2020:chap 29.
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This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
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